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The immunomodulatory effects make this medication a promising treatment agent for autoimmune diseases, infectious diseases, & immune-mediated conditions such as allergies & asthma

An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension

However, the appetite suppression and GI side effects often outweigh potential benefits in patients with poor nutritional status or active disease, requiring careful risk-benefit assessment

The likelihood of gallbladder disease appears to grow with extended treatment durations, making long-term monitoring crucial for users