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It has been reported that Se deficiency is closely related to the occurrence of many diseases in aquatic animals and the impairment of physiological functions under various conditions (Zheng et al., 2018
[1] The active-site Cys residues in the FAD domain and bound NADPH domain are in close proximity removing the necessity for a 66 degree rotation for electron transfer found in E
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Some studies have used doses as high as 4,500 mg per day without serious adverse effects
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