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For how amylin signaling intersects appetite, our references on how cagrilintide is studied in brain satiety circuits and how it affects gastric emptying and postprandial metabolism go deeper into the biology
The interesting science isnt going anywhere
That said, "no serious toxicity in animal models" is not the same as "proven safe in humans long-term," and anyone with a personal or family history of cancer should treat the angiogenic mechanism above as a genuine reason to talk to a qualified clinician before starting
PMID 30845641
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