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The neuroprotective effect of GLP-1RAs through GABAergic modulation not only supports its clinical potential in neurodegenerative diseases such as AD, HD, and Parkinsons diseases (PD), but also adds to our fundamental understanding of GLP-1s pleiotropic molecular network with a special focus on its ocular therapeutic potential

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efocipegtrutide ( LAPS Triple agonist) efpegerglucagon ( LAPS Glucagon analog) HM97662 (EZH1/2 inhibitor) BH3120 (PD-L1/4-1BB BsAb) HM15275 (LA-GLP/GIP/GCG) HM16390 ( LAPS IL-2 analog) HM17321 (LA-UCN2) LAPS Glucagon Combo HM500197 (LA-MSTN) sonefpeglutide ( LAPS GLP-2 analog) Overview First once-a-month injection offering, medical and quality of life benefits sonefpeglutide is a long-acting glucagon-like peptide 2 (GLP-2) analog chemically conjugated with constant region of human immunoglobulin via non-peptidyl flexible linker