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It gives Novo Nordisk an opportunity to remain competitive on efficacy while it continues developing next-generation therapies. Other drugs have already shown greater efficacy in prior studies, and the broader GLP-1 space is likely to see much more significant change as new molecules enter the market. Balazs called the higher dosage a major jump, noting that the incidences of stomach- and skin-related side effects at this higher dose are meaningful. This approval is for obesity management, not diabetes treatment, the expert emphasized

Obesity is a term that can feel subjective

Concurrent medications, particularly those associated with weight gain such as certain antidepressants or antipsychotics, may partially counteract weight loss effects