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In particular, incomplete retrieval of grey literature and insufficient documentation of study-exclusion decisions could lead to overestimation of benefits or underdetection of harms, while the infrequent propagation of primary-study bias into meta-analytic models reduces confidence in the magnitude of pooled effects
While IIH can be a deleterious condition leading to visual worsening or even blindness, it is also associated with reduced quality of life due to severe headache [27]
Several products marketed as natural weight loss aids have been found to contain illicit or previously withdrawn pharmaceutical ingredients, which can lead to serious side effects or dangerous interactions
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