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Additionally, the bacterial lysozyme-like protein LytC_22 binds to Slamf4 on MDSCs, enhancing their immunosuppressive phenotype (increased Arg1 and iNOS), thereby suppressing CD8 T-cell activation and resistance to ICB

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[9] [10] The proposed mechanism centers on the gut microbiome's role in metabolic regulation

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This amplifies workout performance and expedites post-exercise recovery

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