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The data discussed in this review are obtained from previously published studies, which are appropriately cited in the manuscript

N-acetylcysteine (NAC) benefits cystic fibrosis by mitigating oxidative stress and inflammation through antioxidant, anti-inflammatory, and anti-LPS mechanisms, partly via modulation of neurokinin A and IL-6

HABN also increased Lactobacillus abundance (207), complementing the butyrate-mediated Treg activation by Clostridium cluster XIV (192)

In a study of elderly patients by Khavinson et al., Epitalon administration was associated with a 33% reduction in mortality over a 12-year observation period compared with controls, though the study design was not blinded and sample sizes were modest [3]