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FDA The FDA has not endorsed any alternative dosing protocol and has issued warnings about compounded GLP-1 formulations, which are often marketed for microdosing purposes
Two prior authorization policies required at least two comorbidities and 70% of policies specified the conditions
Incompletely established adverse effect profile : Although Phase 2 trial data (NEJM, 2023) provides some safety information, the full adverse effect profile of retatrutide has not yet been established through the complete Phase 3 programme
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