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importantly, in ischemic animals, mannitol accelerated de-ramification of microglia and aggravated inflammation at 3 h but not at 3 days following reperfusion after ischemia
It contains the natural gelling agent guarderived from the guar shrubwhich has been modified by the addition of a hydrophobic end group to form hydroxypropyl guar (HP-guar)
A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood
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