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The following parameters were evaluated and scored on a scale from 0 to 3: 1- Follicular degeneration, 2- Inflammation, 3- Hemorrhage, 4- Edema, 5- Vascular congestion
For example, reduced EAAT2 activity leads to elevated extracellular glutamate concentrations [309, 310], which trigger excessive calcium influx into both neurons and astrocytes
Sikiric, P., et al., A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine
In addition, most of the studies on berberines use in the treatment of neurodegenerative diseases focus on Alzheimers disease and Parkinsons disease, and few other diseases are involved
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