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10.1001/jama.2025.5645 4 AndersenA.KnopF
There are a few FDA-approved options available, such as Zepbound, Wegovy, Nevolat, and Saxenda
Key takeaways: GLP-1 medications are primarily used for weight loss, but are increasingly being explored in relation to PCOS and perimenopause Early evidence (mainly in women with obesity and PCOS) suggests GLP-1s may improve insulin resistance and support more regular menstrual cycles and ovulation There is currently limited research on how GLP-1 medications affect periods, fertility, PMS, or menopause symptoms in the wider population Period tracking apps like Clue may help users monitor cycle and symptom changes while using GLP-1 medications 1
Creatine is a naturally occurring compound synthesised in the body from the amino acids arginine, glycine, and methionine, primarily in the liver and kidneys
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