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In addition, a non-enzymatic product of the prostaglandin D2 synthase gene ( PGD2S ), whose expression is upregulated by acetylcarnitine treatment with 100 mg/kg body weight [134], has been shown to have anti-inflammatory properties that may help protect the brain from ischemiareperfusion injury [72]
Clinical research highlights its ability to promote fibroblast activation, enhance angiogenesis, and modulate gene expression associated with youthful cellular function
Therefore, topical NSAIDs may have advantages over oral NSAIDs in some cases (e.g., osteoarthritis)
2021;34(2):e14776
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