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When REDEFINE 4 results are published, they will provide the first and only direct comparison between these two treatments using the same population, the same endpoints, and the same measurement protocols
J Pharmacol Exp Ther 308 (2): 658666
The peptide enters circulation directly, bypassing digestive processes that can reduce effective doses even for stable compounds
When GSH was tested together with reduced PfGrx C88S or PfGrx C32S/C88S , the syringe of the stopped-flow spectrofluorometer also contained 0.4 U/mL glutathione reductase (GR) and 0.25 mM NADPH to ensure the removal of trace amounts of GSSG that might interfere with the redox measurements
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