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It is approved for type 2 diabetes, but is used off-label for weight loss in overweight or obese patients under medical supervision
The manufacturer of Adlyxin (lixisenatide) recommends taking oral birth control at least one hour prior or 11 hours after lixisenatide for the same reason
This could explain why tirzepatide (which stimulates the GIP pathway in addition to GLP -1) can be administered at higher doses than semaglutide (which only stimulates GLP-1), without amplifying the side effects typical of GLP-1 agonists (nausea, vomiting)
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