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10.1080/21688370.2023.2292461 46 RichardJ

Additionally, trigonelline exhibits notable antioxidant properties, helping to mitigate oxidative stress and protect pancreatic -cells, which are particularly vulnerable to damage in the hyperglycemic environment of diabetes ( Extracts of fenugreek seeds, prepared through aqueous, alcoholic, or hydroalcoholic methods, retain a broad spectrum of bioactive compounds and have been extensively evaluated in diabetic models and clinical trials ( 5.3 Cichorium intybus (chicory) Cichorium intybus , commonly known as chicory, is a perennial herb widely distributed in the Mediterranean and Balkan regions, traditionally used for a variety of medicinal purposes, including the management of diabetes