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In addition to optical isomers, astaxanthin displays geometric (E/Z) isomerism due to multiple conjugated double bonds in its polyene chain, with all-trans (all-E) being the major configuration in nature and 9-cis, 13-cis, and 15-cis isomers reported under certain conditions such as heat or light exposure

Wang Y, Wang D, Zhang Y, Xu H, Shen L, Cheng J, et al

Liver cirrhosis and primary liver cancer Primary liver cancer, as a high incidence of human malignant tumor, lacks typical clinical symptoms in the early stage, but the disease progresses rapidly, has a high risk of death, and the prognosis of patients is generally poor