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[39] The elderly are at increased risk because they tend to produce less stomach acid as they age, a condition known as achlorhydria, thereby increasing their probability of B 12 deficiency due to reduced absorption

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According to doctors, the combination of antidepressants and vitamin B12 leads to an improvement in the condition of patients with depression compared to taking medication alone

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Obeid R, Andrs E, eka R, Hooshmand B, Guant-Rodriguez RM, Prada GI, Sawek J, Traykov L, Ta Van B, Vrkonyi T, Reiners K, The Vitamin B Consensus Panelists Group

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[60] [61] [62] This has led to organizations such as the controversial American Academy of Anti-Aging Medicine promoting the use of this hormone as an "anti-aging agent"

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