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NNMT is upregulated in adipose tissue in obesity, and its inhibition is studied as a potential strategy to modulate NAD+ metabolism and metabolic gene expression
Just how is that
The most-developed and most-distinctive research application for 5-Amino-1MQ is in adipose tissue biology , anchored on a landmark 2014 Nature paper by Kraus and colleagues that established NNMT as a central regulator of adipose energy metabolism
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