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Protocols, as provided in the manufacturers instructions, were followed, including the use of appropriate controls and standards

doi: 10.1371/journal.pone.0021827 277 ToK.CaoR.YegiazaryanA.OwensJ.NguyenT.SasaniniaK.et al

4539-C CMV INFECTION AND ACUTE CELLULAR REJECTION ARE ASSOCIATED WITH RISK OF RECURRENT PRIMARY SCLEROSING CHOLANGITIS AND GRAFT FAILURE AFTER LIVER TRANSPLANTATION Mojmr Hlavat, Lukas Bajer, Jan Brezina, Pavel Wohl, Istvan Modos, Julius Spicak and Pavel Drastich, Institute for Clinical and Experimental Medicine Background: Primary sclerosing cholangitis (PSC) is a chronic liver disease causing inflammation of the bile ducts, forming progressive strictures and stenoses of bile ducts resulting in recurrent cholangitis, liver cirrhosis and death

Under normal circumstances, NRF2 forms a complex with its inhibitory protein, Keap1 which regulates the stability and nuclear translocation of NRF2, thereby controlling its activity