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Endolysosomal zinc dysregulation Defects in the endosomeautophagosomelysosome pathway, the major machinery for degrading protein aggregates and damaged organelles, are central drivers of neurodegenerative diseases such as Alzheimers disease, Parkinsons disease and ALS 166
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However, so far there has not been a perfect model imitating the clinical manifestations of IBS patients
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