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Moreover, MBOAT1 (membrane-bound O-acyltransferase domain-containing 1) and MBOAT2 (membrane-bound O-acyltransferase domain-containing 2), which are transcriptionally upregulated by sex hormone receptors, exert inhibitory effects on ferroptosis in ER + breast cancer and AR + prostate cancer cells, respectively [11]
Such evidence suggests that IF might be integrated as an interventional approach to tackle oxidative stress and inflammatory profiles (Figure 3)
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