Bajpai, So-Young Kim, Yun Suk Huh, Young-Kyu Han, Myunghee Kim Scientific Reports.2019;[Epub] CrossRef Clomiphene promotes browning of white adipocytes via casein kinase-2 inhibition Hyun-Jin Kim, Dong Young Kim, Hyae Gyeong Cheon European Journal of Pharmacology.2019

Dietary modifications form the cornerstone of managing Wegovy-related digestive symptoms: Increase fibre intake gradually through fruits, vegetables, whole grains, and legumes to promote regular, soft bowel movements Maintain adequate hydration (approximately 68 glasses of fluid daily) to prevent constipation and reduce dehydration risk Eat smaller, more frequent meals rather than large portions to reduce nausea and bloating Avoid high-fat, fried, or heavily processed foods that may exacerbate gastrointestinal discomfort Limit carbonated beverages that can increase bloating For constipation specifically , which poses the greatest theoretical risk for haemorrhoid development: Consider osmotic laxatives (e.g., macrogol) as first-line treatment, especially if bloating is present Bulk-forming laxatives (e.g., ispaghula husk) may be helpful but use cautiously if experiencing bloating Establish a regular toilet routine without prolonged sitting or straining Increase physical activity , which promotes intestinal motility Avoid constipating medications where possible (e.g., codeine, some antihistamines) Some patients find that adjusting medication timing helps manage symptoms, though this is not specified in the SmPC

The observational period was relatively short and longer-term data are necessary to fully assess the durability of the observed benefits and long-term safety of both GLP-1 analogues
Still, eat regular meals, avoid crash diets, and report symptoms like sweating, tremors, confusion, or fainting