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Mechanistic studies have found that DHEA modulates insulin signaling pathways, increasing the insulin sensitivity of liver, muscle, and fat cells, which may explain its beneficial metabolic effects (Aoki 2018
Most are "compounded" medications, meaning they are custom-mixed by a pharmacy and have not gone through the FDA's new drug approval process
The adherence challenge is real, but for the patients who tolerate the drugs well and can access them, the data is strong
This guide breaks down every dose of both compounds, maps them against each other week by week, and shows you exactly what the clinical trial data says about outcomes at each level
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