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About 40 percent of this decline is attributable to adaptive thermogenesis, a defensive mechanism in which the body becomes more energy-efficient in response to the perceived shortage
Gln plays a crucial role in the energy supply of rapidly dividing cells, such as intestinal epithelial cells and cells of the immune system 23
The samples were analysed by reversed-phase UPLC (RP-UPLC) at 214 nm and LCMS
There are numerous reasons for an altered microglial secretory profile in aging, but one specific to white matter regions could be an increase in myelin debris that cannot be efficiently cleared/metabolized by microglia, resulting in cellular stress (Safaiyan et al., 2016)
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