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Beyond glucose control, semaglutide addresses multiple cardiovascular risk factors often present in prediabetes, including blood pressure, triglycerides, and systemic inflammation
The STEP 1 trial extension found that patients who discontinued semaglutide after 68 weeks regained approximately two-thirds of their lost weight within 12 months
Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1alpha/glycolysis-dependent axis
Each time the tirzepatide dose increases , the body needs to readjust to stronger appetite suppression, more pronounced gastric slowing, and faster weight loss
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