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Understanding who stands to benefit the most helps allocate this tool where it provides the greatest value
Therefore, maintaining a precisely controlled level of ROS is crucial, as overproduction could disrupt plant defense/tolerance responses and lead to direct and serious damage to cells
The simulated results of molecular docking indicated that GHK-Cu can directly bind to SIRT1 to form a protein complex, and the interacting residues in the complex are composed of GLU-230 and ASN-226 (Figure 5E)
Limitations include: Enzymatic and chemical degradation Poor membrane permeability Comparatively large molecular size When a peptide like epithalon is unmodified, bioavailability may be less than 1%
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