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The decrease of cellular and tissue colonies in states of quiescence is addressed by rapamycin through autophagy
Coprimary end points at week 24 were change from baseline in dysphagia days, measured by a validated patient-reported modified Daily Symptom Diary, and histologic response (peak esophageal eosinophil count 6 per high-power field)
Krammer T, Baier MJ, Hegner P, Zschiedrich T, Lukas D, Wolf M, Le Phu C, Lutz V, Evert K, Kozakov K, Li J, Holzamer A, Maier LS, Provaznik Z, Bers DM, Wagner S, Mustroph J (2025) Cardioprotective effects of semaglutide on isolated human ventricular myocardium
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