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The m6A methyltransferase complex, comprising METTL3, methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit (METTL14), Wilms tumor 1 associated protein (WTAP), and vir-like m6A methyltransferase-associated (VIRMA, previously known as KIAA1429), plays a central role in this process
As with any peptide, understanding the mechanism is only the first step
When the oxygen demand of the cardiac muscle is not met, the cells enter ischemia, which is followed by necrosis (the pathological death of the cells)
Together, these may likely represent the complex way of how the action, which will eventually resolve the lesion, may start and progress
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