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So, theres a lot of enthusiasm, especially given the wild success of Ozempic, but odds are that most of these promising peptides will not work as drugs in humans
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The most recent systematic review, published last year in an orthopaedic journal, screened 544 papers and found one human study that qualified: a retrospective look at 12 people who had the peptide injected into an arthritic knee, seven of whom reported relief lasting more than six months
A 2016 study by Badenhorst and colleagues found that GHK-Cu at its lowest tested concentration (0.01 nanomolar) increased MMP-1 gene expression
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