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Certain factors can increase the chances of having a sulfa allergy, including: A personal or family history of drug allergies Having conditions like HIV, which may increase sensitivity to medications Regular use of antibiotics, which may increase the risk of developing drug allergies over time People who know they have a sulfa allergy should avoid taking sulfa-containing medications unless their doctor gives them specific advice

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The risks associated with B12 therapy apply regardless of whether it's used for approved medical conditions or off-label purposes

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