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doi:10.1016/j.nut.2021.111419

Their ability to regulate metabolic processes and reduce fat accumulation makes them promising candidates for treating liver diseases associated with metabolic syndrome

Interestingly, considering that CCS52B expression is restricted to early phases of the cell cycle (G2/M and M-phase) unlike the A-types (late M-phase to G2-phase) effect of MTX on CCS52B expression goes in accordance with mediation of mitotic cell cycle arrest at S phase