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Key takeaways: First regulatory endorsement linking GLP-1 receptor agonists to MASH treatment Targets adults with non-cirrhotic MASH and moderateadvanced fibrosis Builds on GLP-1 success in obesity and type 2 diabetes Demonstrates histological improvement in liver inflammation and fibrosis Reinforces the role of metabolic pathways in chronic liver disease management This approval signals a shift toward disease-modifying therapies for MASH and highlights how metabolic drugs are reshaping hepatology across Europe

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