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Spitzer et al
Enzyme induction with antiepileptic drugs: cause for concern
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Lipids, especially polyunsaturated fatty acids (PUFAs) in membrane phospholipids, are prime targets for ROS-induced peroxidation ( ROS also damage nucleic acids, particularly guanine bases, resulting in eight-oxoguanine formation, DNA strand breaks, and telomere shortening (Zhou et al., 2025)
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