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I have read claims that B12 is a general detoxifier but there is limited research supporting its direct action as a detoxifer
The intrinsic factor-mediated pathway operates regardless of food presence, and the passive diffusion mechanism (responsible for absorbing about 1% of high doses) similarly functions independently of meals
Nature Reviews Endocrinology, 13(4), 220-231
Many research powders are kept refrigerated or frozen until use
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