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We were able to single out a protein, Med14, whose activation downstream of GLP-1 helps reprogram pancreatic beta cell gene expression to improve the cells viability and insulin production. Often simply called GLP-1 drugs or GLPs, glucagon-like peptide-1 receptor agonists work by mimicking a hormone our bodies naturally make
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One-way ANOVA was used to compare the mean values across multiple groups, followed by Dunnetts test for post hoc multiple comparisons to allowing for a detailed examination of significant differences between different experimental groups
PMID: 25171757
