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For weight management, NICE technology appraisals TA875 (semaglutide/Wegovy) and TA664 (liraglutide/Saxenda) recommend these medications only within specialist weight management services for adults with a BMI 35 kg/m (or 32.5 kg/m in certain ethnic groups) with weight-related comorbidities, and under specific time-limited conditions
PMID 24080311
This is the foundational selectivity paper
doi: 10.1126/sciadv.adi1891 137 ForcinaLMianoCPelosiLMusarA
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