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For some people, they may not experience noticeable changes in appetite or weight changes in the first month
In the SURMOUNT clinical trials for tirzepatide, lean soft tissue loss comprised 26% to 40% of total weight lost
Patients with diabetes face additional risk, as dehydration can precipitate diabetic ketoacidosis in susceptible individuals
It is a co-factor for methionine synthase, an enzyme involved in the methylation cycle, which is crucial for the metabolism of amino acids and the production of neurotransmitters
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