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Genes involved in innate immunity and inflammation, which are lower in Glp1r / at baseline, increases in both WT and Glp1r / in DSS-induced colitis, but differences between genotypes are lost (Yusta et al., 2015)
El diseo del estudio, no orientado al tratamiento de la obesidad, pudo influir en la reduccin ponderal inferior a lo esperado, que no mostr paralelismo con la evolucin de la reduccin de MACE
Most trials are still ongoing and only one prospective randomized clinical trial with a primary outcome of major cardiovascular events in patients with T2D has reported its results [28]
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