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Metabolic Effects of DPP-4 Related to Its Enzymatic Activity Despite DPP-4 having a relatively restricted substrate preference (Figure 1), a large number of peptides, proteins, and chemokines still fulfill the criteria and could be predicted to be suitable substrates, and indeed, many have been shown to be cleaved by DPP-4 in pharmacological kinetic, in vitro or animal studies, often using high substrate concentrations (1, 4, 3638)
Changes in membrane dielectric properties of HL-60 cells during genistein-induced apoptosis-significance in discrimination of apoptotic, necrotic and normal cells
supports connective tissue integrity and promotes deep regeneration at the site of injury or stress
After traumatic brain injury, it counteracts the otherwise progressing course
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