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The rats were randomized equally into four groups: control, model, low dose, and high dose
The gap shows up in month 3-4 and widens through month 12
They are generally recommended for individuals who are overweight or living with obesity and have at least one weight-related comorbidity like high blood pressure or heart disease
While obesity is a chronic disease that may warrant lifelong treatment, the long-term safety, tolerability, and cost of indefinite therapy are not yet established [26, 27]
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