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Interestingly, NKX2-1 alterations are also observed in 12% of lung adenocarcinoma (5) and 16% of neuroendocrine prostate cancer patients (6), and NKX2-1 overexpression is associated with increased expression of serine and glycine synthesis enzymes in these cancer types as well
Intramuscular (IM) Injection: Injected into a muscle, offering a slower release and high absorption rate
3a), and renders the synthesis of cysteine dependent on the activity of one-carbon metabolism (methionine and folate cycles)
J.StromsdorferK
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