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That said, the strongest test of a circulation claim intermittent claudication, or leg pain from reduced blood flow when walking came back negative in the 2013 Cochrane review: no statistically significant improvement in pain-free walking distance vs placebo across pooled trials[7]Ginkgo for Intermittent Claudication Cochrane View source

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Note that for purposes of this article, firms were included in the OTC product category if the warning letter mentioned an OTC product