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Weight can pile back on if you stop using semaglutide drugs Wegovy and Ozempic, doctor warns Those who lose weight using semaglutide are likely to put it back on if they ever stop taking the drug, research shows
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Clinical trials demonstrate significant efficacy, with semaglutide showing average weight loss of approximately 15% in the STEP trials and tirzepatide achieving up to 20% weight loss in the SURMOUNT trials, though individual responses vary considerably
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