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It is unknown whether semaglutide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined.Semaglutide is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Weghuber D, Barrett T, Barrientos-Perez M, Gies I, Hesse D, Jeppesen OK, et al
Retatrutide needs Phase 3 data, FDA approval, cardiovascular outcomes studies, and years of post-market surveillance before it can match semaglutide's evidence base
Additionally, managing stress through relaxation techniques such as meditation or deep breathing can also help alleviate side effects
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