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Chow-fed male C57BL/6J mice at 18 weeks of age were randomly assigned to receive once-daily s.c
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This may explain the comparatively high discontinuation rate of 10.6% for those on the highest dose of orforglipron, a higher figure than the 7% observed for the investigational oral semaglutide
Additionally, it may reduce insulin resistance by lowering insulin levels and supporting better glucose metabolism
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