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Several preclinical studies suggest that GLP-1 receptor agonists increase populations of short-chain fatty acidproducing bacteria

Additionally, SIRT1 modulates the activity of forkhead box O (FOXO) transcription factors, which activate the expression of enzymes involved in ROS detoxification, including SOD2 (superoxide dismutase 2) and catalase, thereby attenuating oxidative stress-induced apoptosis [51]

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Note: Compounded medications are not FDA approved and do not have indications for treatment as an FDA approved medication would