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orlistat, naltrexone/bupropion and phentermine) have a limited role in the management of overweight/obesity in people with or at high risk of CVD due to their minimal impact on weight, unknown CVD benefits and poor tolerability
But for something thats not even FDA-approved yet, like retatrutide, it is only for research purposes, explains Annie Lambert, a pharmacist and compounding specialist with Wolters Kluwer
L., Farzi, A
These findings indicate potential pathways through which incretin therapy may: Stimulate bone formation by activating osteoblasts Inhibit bone resorption via osteoclast suppression Influence calcium and phosphate homeostasis Together, these mechanisms offer biologic plausibility that GLP1 RAs could help preserve bone strength
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