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In addition to its extensively studied actions in peripheral tissues, studies have evaluated the distribution of GLP-1R in the central nervous system (CNS) of rodents, non-human primates, and humans, showing that it is widely diffused to multiple CNS neurons including neurons of the arcuate nucleus (ARC), which are crucial for the control of energy balance (Fig
The rate at which bone is broken down is matched by the rate at which it is rebuilt
Some newer agents act not only on the GLP-1 receptor but also on additional targets, such as the glucose-dependent insulinotropic polypeptide (GIP) receptor
A short course of anti-nausea medication can carry someone through a hard week of titration
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