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The STEP 2 study, a randomized, double-blind, double-dummy, placebo-controlled phase 3 clinical trial reported in The Lancet , involved more than 1,200 adults with Type 2 diabetes who were overweight or obese at the time
In addition to weight reduction, which may increase with longer treatment duration, GIP agonism appears to enhance insulin sensitivity, blood flow, and adipose tissue storage capacity32 (Table 2)
Moreover, it is possible that individuals with NAFLD are more motivated to make positive lifestyle changes, which could have indirect benefits for their overall health, including their response to PBC treatment
Last week in Seattle, researchers from Massachusetts Eye and Ear as well as Havard Medical School presented their findings at ARVO 2024 that highlighted the link between prescribed GLP-1 inhibitors and the development of vision loss due to NAION
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